ResponseNet

ResponseNet is a pathway reconstruction algorithm which finds subnetworks using linear programming, considering an interactome as a way to send ‘flow’ from sources to targets. See the original paper and the corresponding reimplementation of it: https://github.com/Reed-CompBio/ResponseNet.

ResponseNet takes one optional parameter:

• gamma: (int) controls the size of the output graph: more gamma means more ‘flow’ gets passed along starting from the sources.